![]() ![]() ![]() Star-shaped osteoblasts with long, cytoplasmic processes located deep within the lacunae, on which a new osteoid layer has been deposited.On free bony surfaces of the periosteum and endosteum.Control osteoid mineralization ( hydroxyapatite formation).Require alkaline environment ( ↑ pH ) for bone alkaline phosphatase ( ALP ), an enzyme that cleaves inorganic phosphate from various substrates to make it available for mineralization.Produce osteoid (organic bone matrix, mainly composed of collagen ), which is stored in layers on the mineralized matrix.Stimulated by transforming growth factor-beta ( TGF-β), and bone morphogenic proteins.Bone-building cells that differentiate from osteoprogenitor cells. ![]()
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